Judith Hellman, M.D. is the William L. Young, M.D. Endowed Professor and Vice Chair for Research in the UCSF Department of Anesthesia. She is an ICU physician-scientist doing basic-translational research on sepsis and inflammation. The Hellman laboratory uses in vitro and in vivo system to define immunologic mechanisms and to explore immunomodulation in sepsis and in acute and non-acute injury. Current research focuses include understanding the role of Toll-like receptor (TLR) signaling in different cell populations (e.g.: endothelial cells, leukocytes) in sepsis and injury, defining the mechanisms of endothelial activation and dysfunction in sepsis and critical illness, and delineating the immune and functional effects of activation of the endocannabinoid and endovanilloid systems in sepsis, acute inflammation and pain. https://anesthesia.ucsf.edu/research-groups/hellman-lab