Dr. Carolyn Calfee is Professor of Medicine and Anesthesia at the University of California, San Francisco. She is a pulmonary/critical care physician-scientist who leads a translational science laboratory and also cares for patients in the medical intensive care unit. Her group’s research program has three major areas of focus: (1) molecular phenotyping of ARDS and sepsis, with a particular focus on treatment-responsive phenotypes; (2) Phase I, II and III clinical trials in ARDS, sepsis, and related conditions; and (3) the epidemiology and mechanisms of association between tobacco product use and the development of ARDS. 

Her team pioneered the identification of molecular phenotypes in ARDS and sepsis, developing parsimonious models for phenotype identification that are now being implemented in clinical trials, and continues to work to identify key biological differences that characterize these phenotypes in order to inform therapeutic development. She has over 250 peer-reviewed publications and has been continuously funded by the NIH since joining the UCSF faculty in 2007. She currently leads the California Clinical Center and chairs the Science Subcommittee for the NHLBI’s ARDS, Pneumonia and Sepsis Phenotyping Consortium. She also currently serves as an associate editor for the American Journal of Respiratory and Critical Care Medicine.

Dr. Calfee received her medical degree from the University of Pennsylvania School of Medicine and completed her residency, chief residency, and fellowship in pulmonary and critical care medicine at the University of California, San Francisco, where she also earned a Masters in Clinical Research. She is board certified in critical care medicine and pulmonary disease and is an active and dedicated mentor for medical students, residents, fellows, and junior faculty.  Dr. Calfee has received the American Thoracic Society’s Recognition Award for Scientific Accomplishment and is an elected member of the American Society for Clinical Investigation and the Association of American Physicians.  https://calfeelab.ucsf.edu/