Our Mission
The UCSF CPR-CC drives discovery, transforms patient care, and trains the next generation of world-class clinician investigators in critical care medicine. We invest in emerging scientists through funding, mentorship, and career development, while building the collaborative infrastructure that drives innovation in precision critical care to save patient lives in the ICU.
Ongoing Research
What We Do
At CPR-CC, we break down traditional silos by bringing together experts in pulmonary, cardiology, anesthesia, surgery, and beyond – harnessing their collective expertise to transform care for critically ill patients.
Pilot Grants
Funding for early career investigators
Coaching & Mentorship
Research methods, computational biology, database design, biospecimen banking
Shared Resources
Integrating critical care research across divisions and departments
Collaboration Hub
Connecting clinicians, bedside providers, and researchers to advance precision approaches to critical care
Events & Seminars
Stay tuned for upcoming CPR-CC seminars and research talks featuring UCSF faculty and guest experts in critical care medicine. Our seminar series will launch in 2026.
Coming Soon
Coming Soon
Coming Soon
Patient & Researcher Stories
Dr. Jon Singer
Originally featured by UCSF Health: ‘Catching His Breath’
“The story follows Bradley Dell, a young man who suffers from severe cystic fibrosis. The Hawaii native becomes so sick that his survival depends on whether he gets a double-lung transplant. Unfortunately, because he has a super bacterial infection, hospitals across the country turn him down for the surgery. When the UCSF transplant team learns about Bradley’s case, they realize they need to push the boundaries of what defines a transplant candidate.”
Bradley’s care and recovery involved members of the CPR-CC Core Faculty, including Dr. Jon Singer, whose research in patient-center outcomes in lung transplantation and cystic fibrosis continues to advance outcomes for patients with advanced lung disease and transplant cared for in intensive care units.
Dr. Lucy Kornblith
"My work is inspired by the urgency and human cost of traumatic injury, especially how bleeding and blood-system failure contribute to preventable deaths. At the Kornblith Lab we investigate the cellular and molecular mechanisms underlying trauma-induced coagulopathy, with the goal of identifying new diagnostic markers and therapeutic targets. We combine basic and translational science, large observational cohorts, and clinical trials to bridge mechanistic insight with real-world patient care. Research collaborations are essential: they allow us to access complementary expertise (in biostatistics, vascular biology, critical care, and beyond) and to assemble the patient cohorts and biospecimens necessary to test hypotheses in real injured populations." -Lucy Kornblith
Dr. Carolyn Calfee & Dr. Michael Matthay
On October 21, 2025, Dr. Carolyn Calfee and Dr. Michael Matthay, Co-Founders and Directors of the CPR-CC, presented at the UCSF Department of Medicine Grand Rounds.
Their talk, “ARDS: New Global Definition, Current Therapies, and Implementing Precision Critical Care,” reviewed the recently updated global definition of Acute Respiratory Distress Syndrome (ARDS) and discussed how emerging research and precision approaches are shaping the future of care for critically ill patients.
This presentation reflects the mission of the CPR-CC of bringing cutting-edge science to the bedside and improve outcomes for patients facing life-threatening illness.
Watch the full presentation here: ARDS: New Global Definition, Current Therapies, and Implementing Precision Critical Care
Dr. Matt Zinter
“Working as a pediatric critical care physician at UCSF offers a unique opportunity to combine compassionate, high-stakes clinical care with scientific progress. The children we care for often face the most complex and life-threatening illnesses, requiring the coordinated expertise of specialists across disciplines. Partnering with world-class physicians and scientists allows us to push the boundaries of what is possible—to uncover new mechanisms of disease, personalize treatments, and translate emerging research directly into better outcomes. It is deeply meaningful work that unites purpose, innovation, and hope for children and their families. Our pediatric-focused team offers more than 20 clinical studies including clinical trials that offer specialized treatment available only at UCSF.” -Matt Zinter